Role for mannose binding lectin in the prevention of Mycoplasma infection.
نویسندگان
چکیده
Polymorphisms in exon 1 of the MBL-2 gene, resulting in reduced plasma levels of mannose binding lectin, were significantly overrepresented in 23 patients with primary antibody deficiency and culture-proven mycoplasma infections (P = 0.0038). This association persisted with the inclusion of a further nine suspected (doxycycline-responsive) cases (P = 0.0087). The lectin was shown to bind to three strains of mycoplasma.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 73 8 شماره
صفحات -
تاریخ انتشار 2005